Yeah I didn't like Mr X, the dramatic music and the fact that he literally only staggered with a shot from the Magnum had me terrified of him. But Lisa, nothing really works on her. Even if you unlock the Rocket Launcher and shoot her with it, it just swats that bitch into a wall and she's back on her feet.
I mean, you can't say that she wasn't legtimately terrifying. When Wesker goes missing in the Hall and you check the gates beneath the stairs, and all you hear is her wailing and the chains being dragged along the floor, it creeps the absolute fuck out of you.